In addition to mandatory tests:

• Persistent pupillary membranes (PPM)(PPM)

  Augen und Sehvermögen

  Persistent pupillary membranes (PPM) occur when tiny blood vessels that nourish the eye's lens before birth fail to break down and disappear as they normally should. This leaves behind delicate strands of tissue that stretch across the iris, which is the colored part of the eye, and the pupil. In some cases, these strands can attach to the cornea, the clear outer layer of the eye, or the lens.

  Augen · Passing: Clear

  Deep dive+

• Legg-Calvé-Perthes disease(LCPD)

  Bewegungsapparat

  Legg-Calvé-Perthes disease is a serious orthopedic condition affecting the hip joint, primarily in small breed dogs. It occurs when the blood supply to the head of the thigh bone, known as the femur, is spontaneously disrupted. Without blood, this bone tissue dies and collapses, leading to severe joint inflammation and pain.

  Roentgen · Passing: A

  Deep dive+

• Atopy(CAD)

  Haut und Fell

  Atopy is a chronic allergic skin disease where a dog's immune system overreacts to common environmental substances like pollen, mold spores, and dust mites. This inappropriate immune response damages the natural protective barrier of the skin, leading to persistent inflammation and irritation. It primarily affects the skin, which is the body's largest organ system.

  Haut

  Deep dive+

• Epidermal dysplasia

  Haut und Fell

  Epidermal dysplasia, also known as Westie Armadillo Syndrome or hyperplastic dermatosis, is an inherited skin disorder where the outer layers of the skin do not develop or mature properly. This defect compromises the skin's natural protective barrier, making it highly vulnerable to secondary yeast and bacterial infections. The condition primarily affects the integumentary (skin) system, leading to chronic, severe inflammation.

  Haut · Passing: CLEAR

  Deep dive+

• Ichthyosis(ICT)

  Haut und Fell

  Ichthyosis is an inherited skin disorder where the outer layer of the skin, the epidermis, does not develop or shed properly. This defect in keratinization—the process of forming a protective outer skin barrier—leads to a buildup of dry, thick, and scaly skin. Because this barrier is compromised, the dog's body is more vulnerable to secondary infections.

  Passing: CARRIER

  Deep dive+

• Pulmonary stenosis(PS)

  Herz

  Pulmonary stenosis is a congenital heart defect characterized by a narrowing of the pulmonary valve or the outflow tract leading from the heart to the lungs. This narrowing restricts blood flow, forcing the right side of the heart to work much harder to pump blood. Over time, this constant strain can lead to thickening of the heart muscle and potential heart failure.

  Passing: NORMAL

  Deep dive+

• Pyruvate kinase (PK) deficiency(PKD)

  Herz und Kreislauf

  Pyruvate kinase (PK) deficiency is an inherited metabolic disorder affecting red blood cells, which lack a vital enzyme needed to produce energy. Without this enzyme, the red blood cells break down prematurely, leading to a severe shortage of oxygen-carrying cells, a condition known as chronic anemia. Over time, this constant cell destruction can cause secondary damage to organs like the liver and bone marrow.

  DNA · Passing: CARRIER

  Deep dive+

• Congenital deafness(CHSD)

  Nervensystem

  Congenital deafness is a hereditary hearing loss present from birth that affects the inner ear's sensory cells, preventing sound signals from reaching the brain. It is often linked to specific genetic variants, such as those associated with certain coat patterns like merle or piebald, or breed-specific conditions like Early Onset Adult Deafness (EOAD). This genetic defect causes the vital blood supply to the inner ear to fail, leading to the permanent degeneration of the hearing nerve cells.

  Physisch · Passing: BILATERAL_HEARING

  Deep dive+

• Globoid cell leukodystrophy (galactocerebrosidosis)(GCL)

  Nervensystem

  Globoid cell leukodystrophy is an inherited metabolic disorder affecting the nervous system, caused by a deficiency in an essential enzyme. This deficiency leads to the buildup of harmful substances that destroy myelin, which is the protective sheath surrounding nerve fibers in the brain and spinal cord. Without this protective covering, the nerves cannot transmit signals properly, resulting in progressive neurological decline.

  DNA · Passing: CARRIER

  Deep dive+

• Shaker dog syndrome(GTS)

  Nervensystem

  Shaker dog syndrome is an inflammatory condition affecting the cerebellum, which is the part of the brain responsible for coordinating voluntary muscle movements. This inflammation, believed to be an immune-mediated response where the body's immune system mistakenly attacks its own nervous tissue, leads to uncontrollable full-body tremors. The exact underlying cause of this brain inflammation remains unknown.

  Roentgen · Passing: B

  Deep dive+

• Chronic hepatitis(CH)

  Stoffwechsel

  Chronic hepatitis is a long-term, progressive inflammation of the liver, which is the organ responsible for filtering toxins and processing nutrients. This ongoing inflammation damages the liver tissue over time and can eventually lead to liver failure. It is often caused by genetic predispositions that lead to abnormal copper buildup in the liver, or by abnormal immune system responses.

  Koerperfluessigkeiten · Passing: CARRIER

  Deep dive+