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We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 4 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Osteochondritis dissecans(OCD)
Bewegungsapparat
Osteochondritis dissecans (OCD) is a developmental skeletal disorder affecting the joints, where a piece of cartilage fails to turn into bone properly. This abnormal cartilage can crack and detach from the underlying bone, creating a loose flap or fragment that floats in the joint space. This leads to painful inflammation and joint damage, most commonly in the shoulders, elbows, or knees.
Roentgen · Passing: 0
Heart disease
Herz
Heart disease refers to structural or functional abnormalities of the heart muscle, valves, or electrical system that impair its ability to pump blood effectively. This reduced pumping efficiency prevents the cardiovascular system from delivering adequate oxygen and nutrients to the body's tissues. Some forms are congenital, meaning present from birth, while others are acquired over time due to wear or genetic factors.
Physisch · Passing: NORMAL
Degenerative Myelopathy(DM)
Nervensystem
Degenerative Myelopathy is a progressive disease of the spinal cord where the protective sheath around the nerves slowly breaks down. This deterioration disrupts the vital communication signals between the brain and the muscles of the hind limbs. Over time, this lack of signal transmission leads to a complete loss of muscle control in the back legs.
DNA · Passing: Clear or Carrier
Hyperuricosuria(HUU)
Nieren
Hyperuricosuria is an inherited metabolic disorder affecting the renal system, specifically how the kidneys process uric acid. Due to a genetic mutation, excess uric acid is excreted into the urine rather than being broken down. This high concentration can cause the acid to crystallize, leading to the formation of painful bladder or kidney stones, also known as uroliths.
Koerperfluessigkeiten · Passing: Clear or Carrier
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Dental-skeletal-retinal anomaly
Both parents must be Clear or Carrier or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH-Zuchtordnungen, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
4 tests are currently mandatory under the relevant breed-club regulations. The most common are Dental-skeletal-retinal anomaly (DSRA), Elbow Dysplasia (ED), Hip dysplasia (HD). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breedersHealth Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Cane Corso we have compiled 4 mandatory and 4 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
As a large and heavy breed, the Cane Corso frequently suffers from joint issues such as hip dysplasia (HD) and elbow dysplasia (ED), which is why radiographic screenings are essential before breeding. Additionally, Dental-skeletal-retinal anomaly (DSRA) poses a breed-specific risk, though this can be managed through targeted genetic testing. Without consistent selective breeding, there is an increased risk of painful skeletal disorders.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Cane Corso we track 4 mandatory tests plus 4 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.