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We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 9 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Brachyury(NBT)
Allgemeine Fitness und Anatomie
Brachyury is a congenital condition affecting the skeletal system where a dog is born with an unusually short or completely absent tail. It is caused by an autosomal-dominant genetic mutation in the T-box gene, which plays a key role in embryonic skeletal development. This mutation alters how the tail vertebrae form before birth, resulting in a naturally bobbed tail.
Physisch · Passing: CARRIER
Collie eye anomaly (CEA)(CEA)
Augen
Collie Eye Anomaly is an inherited developmental defect affecting the eye, specifically the retina (the light-sensitive tissue at the back of the eye) and the choroid (the underlying layer of blood vessels). This genetic condition causes these structures to develop abnormally before birth. It is primarily seen in herding breeds and is inherited in an autosomal recessive manner.
Passing: CARRIER
Cone Degeneration(CD)
Augen
Cone degeneration is an inherited eye disorder where the specialized light-sensitive cells in the retina responsible for color and bright light vision, called cones, gradually break down. This deterioration specifically affects the dog's ability to see in daylight, while the rod cells, which handle low-light and night vision, remain completely healthy and functional.
DNA · Passing: CARRIER
Distichiasis
Augen und Sehvermögen
Distichiasis is an eye condition where extra eyelashes grow from the meibomian glands, which are the oil glands along the edge of the eyelid. These abnormal hairs point inward and rub directly against the cornea, the clear outer surface of the eye. This constant friction causes mechanical irritation and can damage the sensitive ocular surface.
Augen · Passing: AFFECTED
Chondrodysplasia, SLC13A1-related
Bewegungsapparat
This is an inherited form of dwarfism affecting the skeletal system, specifically bone and cartilage development. It is caused by a genetic mutation that leads to a deficiency in sulfate, a compound crucial for healthy bone growth. Without enough sulfate, the dog's skeleton cannot develop to its normal size and structure.
Passing: CLEAR
Elbow Dysplasia(ED)
Bewegungsapparat
Elbow dysplasia is a developmental disorder of the musculoskeletal system where the three bones forming the elbow joint do not fit together properly. This misalignment causes abnormal friction and wear on the joint cartilage, eventually leading to painful, chronic joint inflammation and arthritis. It is a complex genetic condition influenced by multiple genes.
Roentgen · Passing: 0
Patellar Luxation(PL)
Bewegungsapparat
Patellar luxation, also known as a luxating patella, is a physical condition affecting the knee joint where the kneecap slips out of its normal groove. This misalignment interferes with the mechanical movement of the hind leg and can cause the joint to lock. Over time, this abnormal friction can lead to painful joint wear and tear, known as osteoarthritis.
Physisch · Passing: 1
Degenerative Myelopathy(DM)
Nervensystem
Degenerative Myelopathy is a progressive disease of the spinal cord where the protective sheath around the nerves slowly breaks down. This deterioration disrupts the vital communication signals between the brain and the muscles of the hind limbs. Over time, this lack of signal transmission leads to a complete loss of muscle control in the back legs.
DNA · Passing: CLEAR
Hyperuricosuria(HUU)
Nieren
Hyperuricosuria is an inherited metabolic disorder affecting the renal system, specifically how the kidneys process uric acid. Due to a genetic mutation, excess uric acid is excreted into the urine rather than being broken down. This high concentration can cause the acid to crystallize, leading to the formation of painful bladder or kidney stones, also known as uroliths.
Koerperfluessigkeiten · Passing: CARRIER
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Progressive Retinal Atrophy (PRA)
Both parents must be CARRIER or better.
We compile mandatory tests from official breed regulations and veterinary databases — and check every uploaded certificate for authenticity.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH-Zuchtordnungen, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and reviewed by our team for authenticity, date, and result.
8 tests are currently mandatory under the relevant breed-club regulations. The most common are Progressive Retinal Atrophy (PRA) (PRA), Retinal Dysplasia (RD), Cataract (HC). Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
See breeders who have already uploaded their mandatory tests for verification.
View verified breedersHealth Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Miniature American Shepherd we have compiled 8 mandatory and 9 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
With 17 mandatory health tests, the Miniature American Shepherd carries an above-average genetic burden that requires very careful breeding selection. While critical conditions like Multidrug-Resistance 1 (MDR1) and Collie Eye Anomaly (CEA) can be effectively managed through genetic testing, more serious issues such as hip dysplasia (HD) and unpredictable epilepsy remain a risk. Prospective buyers should be extremely meticulous in ensuring that the parents have complete and verified health certificates.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Miniature American Shepherd we track 8 mandatory tests plus 9 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.