Combined Pituitary Hormone Deficiency · POU1F1 pituitary dwarfism · Pituitary Dwarfism POU1F1-related
This is an inherited disorder affecting the pituitary gland, which is a small hormone-producing organ at the base of the brain. Due to a genetic mutation, this gland fails to produce essential hormones, specifically growth hormone and thyroid-stimulating hormone. This deficiency severely disrupts the dog's normal growth, metabolism, and physical development.
Owners typically notice symptoms in puppies around 3 to 4 weeks of age. Signs include severely stunted growth, a lack of normal adult coat development leading to hair loss, and extreme lethargy or sluggishness.
The condition is not curable and requires lifelong hormone replacement therapy alongside regular veterinary monitoring. This intensive treatment is estimated to cost between 4,000 and 12,000 EUR over the dog's lifetime.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Hips.