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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Samoyed we've compiled 10 core tests (1 of them required by Deutscher Club für Nordische Hunde e.V. (DCNH)) and 18 additionally recommended tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
View verified breedersWhat this grade means
In the Samoyed, breed-specific risks exist for eye diseases such as pectinate ligament dysplasia (PLD), primary lens luxation (PLL), and cataract, as well as for hip dysplasia (HD). The Deutscher Club für Nordische Hunde e.V. (DCNH) mandatorily requires proof that the parent animals are free from pectinate ligament dysplasia (PLD). A health-oriented breeder additionally tests the parent animals for hip dysplasia (HD) with the cut-off value HD A–C, as well as for primary lens luxation (PLL) and cataract (free in each case). Make sure that these test results and ideally genetic tests for familial nephropathy (FN) are available to you – carriers may only be mated with free partners.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. The core standard for the Samoyed covers 10 tests, 1 of them required by Deutscher Club für Nordische Hunde e.V. (DCNH), plus 18 additional recommended tests. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions don't always predict severity in the puppies. Even so, they're a powerful tool of responsible breeding.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level meets the Good level and performs 18 additional clinically recommended screenings that reduce risk in this breed.
In addition to Good:
Amelogenesis Imperfecta (Enamel Hypoplasia)(AI)
Andere
This is an inherited genetic disorder affecting the dental system, specifically the development of tooth enamel. Due to a genetic mutation, the protective outer layer of the teeth (enamel) does not form properly or is completely missing. This leaves the softer, underlying layers of the teeth exposed, making them fragile and highly sensitive.
Physical examination · Passing: clear or carrier
Corneal dystrophy(CD)
Augen
Corneal dystrophy is an inherited eye disorder where abnormal, opaque materials like fats or calcium build up in the cornea, which is the clear outer layer of the eye. This accumulation typically affects both eyes and is non-inflammatory, meaning it does not cause immediate swelling or redness. Over time, these deposits can disrupt the smooth surface of the eye.
Eye examination · Passing: clear
Primary Open-Angle Glaucoma(POAG)
Augen
Primary open-angle glaucoma is an inherited eye disease where the natural fluid inside the eye cannot drain properly. This fluid buildup causes a gradual increase in pressure within the eyeball, which eventually damages the optic nerve, the connection between the eye and the brain. Without management, this pressure leads to permanent blindness.
Eye examination · Passing: clear
Progressive Retinal Atrophy (PRA)(PRA)
Augen
Progressive Retinal Atrophy (PRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer of tissue at the back of the eye. In this condition, the specialized cells responsible for detecting light, known as photoreceptors, gradually degenerate and die. Because these cells cannot recover or be replaced, the disease slowly but inevitably leads to complete blindness.
Passing: clear or carrier
Chondrodysplasia, SLC13A1-related
Bewegungsapparat
This is an inherited form of dwarfism affecting the skeletal system, specifically bone and cartilage development. It is caused by a genetic mutation that leads to a deficiency in sulfate, a compound crucial for healthy bone growth. Without enough sulfate, the dog's skeleton cannot develop to its normal size and structure.
Passing: clear or carrier
Duchenne muscular dystrophy(DMD)
Bewegungsapparat
This is a severe, inherited muscle disorder caused by a lack of dystrophin, which is a crucial protein that helps keep muscle cells intact. Without this protein, both the skeletal muscles used for movement and the cardiac muscle of the heart progressively weaken and break down.
DNA test · Passing: clear
Sebaceous Adenitis(SA)
Haut und Fell
Sebaceous adenitis is an inflammatory skin disorder where the dog's immune system mistakenly attacks and destroys the sebaceous glands, which are the glands responsible for producing natural skin oils. Without these oils, the skin loses its protective moisture barrier, leading to severe dryness and damage to the hair follicles.
Growth hormone-responsive dermatosis; adrenal sex hormone-responsive dermatosis
Haut und Fell
This is a hormonal skin condition affecting the endocrine system, where an imbalance in adrenal sex hormones or a lack of growth hormone leads to symmetrical hair loss. The skin's hair follicles stop producing new hair, causing them to enter a permanent resting phase. While the skin and coat are affected, the dog's internal organs and overall physical health typically remain completely normal.
Body-fluid analysis
Zinc-responsive dermatosis(ZRD)
Haut und Fell
Zinc-responsive dermatosis is a skin disorder where a dog's body cannot properly absorb or use zinc from their food, even when eating a balanced diet. This nutritional deficiency weakens the skin's protective barrier, leading to irritation and abnormal skin cell development. Because there are no genetic tests for this condition, veterinarians diagnose it using breed history, skin biopsies, and how well the dog responds to zinc therapy.
Skin test
Aortic valve stenosis(AS)
Herz
Aortic stenosis is a narrowing of the aortic valve in the heart, which controls blood flow from the main pumping chamber (the left ventricle) to the rest of the body. Because of this restriction, the heart muscle must work much harder to pump blood, which eventually causes the muscle wall to thicken abnormally. This is a severe cardiovascular condition that can strain the heart over time.
Passing: normal
Pulmonary stenosis(PS)
Herz
Pulmonary stenosis is a congenital heart defect characterized by a narrowing of the pulmonary valve or the outflow tract leading from the heart to the lungs. This narrowing restricts blood flow, forcing the right side of the heart to work much harder to pump blood. Over time, this constant strain can lead to thickening of the heart muscle and potential heart failure.
Passing: normal
Atrial septal defect(ASD)
Herz
An atrial septal defect is a congenital heart condition where a hole exists in the wall, called the septum, that separates the two upper chambers of the heart. This opening allows blood to flow abnormally between these chambers, which can gradually place extra strain on both the heart and the lungs.
Passing: normal
Congenital deafness(CHSD)
Nervensystem
Congenital deafness is a hereditary hearing loss present from birth that affects the inner ear's sensory cells, preventing sound signals from reaching the brain. It is usually genetic, occurs more often in certain breeds and is frequently linked to coat patterns such as merle or piebald.
Physical examination · Passing: hearing in both ears
Globoid cell leukodystrophy (galactocerebrosidosis)(GCL)
Nervensystem
Globoid cell leukodystrophy is an inherited metabolic disorder affecting the nervous system, caused by a deficiency in an essential enzyme. This deficiency leads to the buildup of harmful substances that destroy myelin, which is the protective sheath surrounding nerve fibers in the brain and spinal cord. Without this protective covering, the nerves cannot transmit signals properly, resulting in progressive neurological decline.
DNA test · Passing: clear or carrier
Hypomyelination(HYM)
Nervensystem
This is an inherited neurological disorder affecting the central nervous system, where the protective myelin sheath that insulates nerve fibers fails to develop properly. Without this adequate insulation, nerve signals cannot travel efficiently between the brain and the body. This disruption leads to impaired coordination and involuntary muscle movements.
Passing: clear
Cerebellar abiotrophy(CA)
Nervensystem
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
DNA test · Passing: clear
Familial Nephropathy(FN)
Nieren
Familial Nephropathy (FN) is an inherited kidney disease caused by a genetic defect in collagen, which is a vital structural protein. This defect damages the kidneys' filtering units, preventing them from properly removing waste products from the blood. Over time, this leads to progressive and irreversible kidney failure.
Body-fluid analysis · Passing: clear or carrier
Hemophilia
Stoffwechsel
Hemophilia is an inherited blood clotting disorder affecting the circulatory system, where the body lacks specific proteins needed for coagulation, which is the process of blood clotting. Because the blood cannot clot properly, even minor injuries can lead to prolonged internal or external bleeding. This condition is inherited through an X-linked genetic trait, meaning it primarily affects male dogs.
Body-fluid analysis · Passing: clear
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every core-standard and additionally recommended test, plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Distichiasis
Both parents must be clear or better.
We take mandatory tests from official breed regulations, build the recommended health standard from veterinary databases — and cross-check every uploaded certificate against the dog's profile using AI.
L1 = core standard: the club's required tests where its rules set them, otherwise the recommended health standard for the breed. L2 = additionally recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are read by AI and checked for date, result, and consistency with the dog's profile — our team reviews anything inconclusive.
The Samoyed is not currently listed in our extreme-breeding overview. That does not mean it is free of hereditary disease: which ones are typical, and which tests the parents should have, is on this page.
Self-check
Answer 6 quick questions about your everyday life and see how well the Samoyed fits you — including an honest cost estimate per month, per year, and across the dog's lifetime.
See breeders who have already uploaded their health test results for verification.
View verified breeders