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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Shar-Pei we've compiled 6 tests required by 1. Deutscher Shar-Pei Club 1985 e.V. and 10 additionally recommended tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
View verified breedersWhat this grade means
In the Shar Pei, Familial Shar-Pei Fever occurs with increased frequency; in the long term, it can lead to kidney damage via amyloidosis, and the breed also frequently struggles with problems such as ectropion / entropion as well as joint dysplasias. The 1. Deutscher Shar-Pei Club 1985 e.V. therefore mandates mandatory examinations for hip dysplasia (HD), elbow dysplasia (ED), ectropion / entropion, autoinflammatory disease (Shar-Pei), and genetic testing for primary open-angle glaucoma and primary lens luxation (PLL). A health-oriented breeder additionally tests for risks such as brachycephalic obstructive airway syndrome (BOAS) or progressive retinal atrophy (prcd-PRA). Before buying a puppy, have the official certificates shown to you: For PLL and primary open-angle glaucoma, carriers may only be mated with demonstrably clear partners, and for HD, results from HD A to C at most are permissible (C only with A).
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Shar-Pei, 1. Deutscher Shar-Pei Club 1985 e.V. requires 6 tests for breeding approval, plus 10 additional recommended tests. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions don't always predict severity in the puppies. Even so, they're a powerful tool of responsible breeding.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level meets the Good level and performs 10 additional clinically recommended screenings that reduce risk in this breed.
In addition to Good:
Cleft palate
Andere
A cleft palate is a congenital birth defect where the roof of the mouth fails to fuse properly during development in the womb. This failure leaves an abnormal opening between the oral cavity and the nasal passages. Because these two systems are directly connected, food, liquids, and air cannot be properly separated during swallowing.
Physical examination · Passing: clear
Megaesophagus(ME)
Andere
Megaesophagus is a disorder of the digestive system where the esophagus, the muscular tube connecting the throat to the stomach, becomes abnormally stretched and loses its muscle tone. Because these muscles can no longer contract to push food and liquid downward, meals become trapped in the tube. This trapped material is typically regurgitated, meaning it is passively cast back up before ever reaching the stomach.
X-ray
Brachycephalic obstructive airway syndrome (BOAS)(BOAS)
Atmung
Brachycephalic obstructive airway syndrome (BOAS) is a severe respiratory condition affecting short-muzzled dog breeds, where the physical shortening of the skull leaves insufficient space for the upper airways. This structural compression forces tissues like the soft palate and nasal passages into a restricted area, significantly obstructing the flow of oxygen to the lungs. Over time, the increased effort required to breathe puts chronic strain on the dog's respiratory and cardiovascular systems.
Physical examination
Cataract(HC)
Augen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Eye examination
Progressive rod-cone degeneration (PRCD-PRA)(PRA-prcd)
Augen
This is an inherited eye disease where the light-sensitive cells in the retina, called rods and cones, slowly break down over time. The rods, which handle vision in dim light, degenerate first, followed by the cones, which are responsible for bright light and color vision. This gradual degeneration of the eye's sensory layer eventually leads to complete blindness.
Passing: clear or carrier
Patellar Luxation(PL)
Bewegungsapparat
Patellar luxation, also known as a luxating patella, is a physical condition affecting the knee joint where the kneecap slips out of its normal groove. This misalignment interferes with the mechanical movement of the hind leg and can cause the joint to lock. Over time, this abnormal friction can lead to painful joint wear and tear, known as osteoarthritis.
Physical examination · Passing: PL 0
Atopy(CAD)
Haut und Fell
Atopy is a chronic allergic skin disease where a dog's immune system overreacts to common environmental substances like pollen, mold spores, and dust mites. This inappropriate immune response damages the natural protective barrier of the skin, leading to persistent inflammation and irritation. It primarily affects the skin, which is the body's largest organ system.
Skin test
Demodicosis / Demodectic mange
Haut und Fell
Demodicosis is a skin disease caused by an overgrowth of microscopic Demodex mites that naturally live inside a dog's hair follicles. While these mites are normally harmless, an inherited or acquired weakness in the immune system can allow them to multiply uncontrollably. This overgrowth leads to inflammation and damage to the skin barrier.
Skin test
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physical examination · Passing: General breeding exclusion
Familial Nephropathy(FN)
Nieren
Familial Nephropathy (FN) is an inherited kidney disease caused by a genetic defect in collagen, which is a vital structural protein. This defect damages the kidneys' filtering units, preventing them from properly removing waste products from the blood. Over time, this leads to progressive and irreversible kidney failure.
Body-fluid analysis
Not health tests, but required for breeding: the club asks for these results too. They don't count toward the risks or the rating.
DNA-Identitätsnachweis
Required by 1. Deutscher Shar-Pei Club 1985 e.V.
Acceptable result: Nachweis eines ISAG2020 Profils (oder ISAG2006 Profils)
Wesensbeurteilung
Required by 1. Deutscher Shar-Pei Club 1985 e.V.
Acceptable result: Bestehen der ZZP (zuchttauglich ohne Auflagen, mit Auflagen oder bedingt zuchttauglich)
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every core-standard and additionally recommended test, plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Hip dysplasia
Both parents must be HD A–C (C only with A) or better.
We take mandatory tests from official breed regulations, build the recommended health standard from veterinary databases — and cross-check every uploaded certificate against the dog's profile using AI.
L1 = core standard: the club's required tests where its rules set them, otherwise the recommended health standard for the breed. L2 = additionally recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are read by AI and checked for date, result, and consistency with the dog's profile — our team reviews anything inconclusive.
These hereditary conditions are currently classified as most relevant for the Shar-Pei: Ectropion / Entropion, Lens luxation (PLL), Primary Open-Angle Glaucoma (POAG), Elbow Dysplasia (ED), Hip dysplasia (HD), Shar-Pei Autoinflammatory Disease (SPAID) (SPAID). The risk for a puppy depends primarily on whether both parents have been tested for these conditions and whether the results fall within breed-specific requirements.
Self-check
Answer 6 quick questions about your everyday life and see how well the Shar-Pei fits you — including an honest cost estimate per month, per year, and across the dog's lifetime.
See breeders who have already uploaded their health test results for verification.
View verified breeders