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Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Sheepadoodle we have compiled 0 mandatory and 22 recommended health tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
What this grade means
As a crossbreed between an Old English Sheepdog and a Poodle, the Sheepadoodle benefits from heterosis, as homozygous gene mutations from one parent often remain unexpressed in the offspring. Nevertheless, risks for joint diseases such as hip dysplasia and eye conditions like progressive retinal atrophy and cataracts persist if both parents carry the genetic traits. Additionally, neurological and autoimmune diseases occur in isolated cases. Health-focused breeding relies on comprehensive genetic testing of the parent dogs as well as X-ray examinations of the joints to deliberately minimize risks.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Sheepadoodle we track 0 mandatory tests plus 22 additional recommended ones. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions are not always predictive of severity in the puppies. Even so, they're a powerful tool used by every responsible breeder.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level performs all mandatory tests plus 22 additional clinically recommended screenings that reduce risk in this breed.
In addition to mandatory tests:
Cleft palate
Allgemeine Fitness und Anatomie
A cleft palate is a congenital birth defect where the roof of the mouth fails to fuse properly during development in the womb. This failure leaves an abnormal opening between the oral cavity and the nasal passages. Because these two systems are directly connected, food, liquids, and air cannot be properly separated during swallowing.
Physisch
Immune-mediated hemolytic anemia (IMHA)(IMHA)
Andere
Immune-mediated hemolytic anemia (IMHA) is a severe condition where the dog's immune system mistakenly identifies its own red blood cells as foreign threats and destroys them. Because red blood cells are responsible for carrying oxygen, this destruction leads to a critical oxygen shortage throughout the body's organs. This disease primarily impacts the immune and circulatory systems.
Koerperfluessigkeiten
Primary ciliary dyskinesia (PCD), NME5-related(PCD)
Atmung
Primary ciliary dyskinesia is an inherited respiratory disease caused by a genetic mutation that affects the cilia, which are tiny, hair-like structures lining the airways. In affected dogs, these cilia are malformed or unable to move properly, preventing them from clearing mucus, dust, and bacteria out of the lungs and nasal passages. This failure of the respiratory clearance system leads to chronic airway irritation and recurrent infections.
Progressive Retinal Atrophy (PRA)(PRA)
Augen
Progressive Retinal Atrophy (PRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer of tissue at the back of the eye. In this condition, the specialized cells responsible for detecting light, known as photoreceptors, gradually degenerate and die. Because these cells cannot recover or be replaced, the disease slowly but inevitably leads to complete blindness.
Progressive rod-cone degeneration (PRCD-PRA)(PRA-prcd)
Augen
This is an inherited eye disease where the light-sensitive cells in the retina, called rods and cones, slowly break down over time. The rods, which handle vision in dim light, degenerate first, followed by the cones, which are responsible for bright light and color vision. This gradual degeneration of the eye's sensory layer eventually leads to complete blindness.
Cataract(HC)
Augen und Sehvermögen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Augen
Elbow Dysplasia(ED)
Bewegungsapparat
Elbow dysplasia is a developmental disorder of the musculoskeletal system where the three bones forming the elbow joint do not fit together properly. This misalignment causes abnormal friction and wear on the joint cartilage, eventually leading to painful, chronic joint inflammation and arthritis. It is a complex genetic condition influenced by multiple genes.
Roentgen · Passing: FCI-Grad 0 (ED-frei)
Hip dysplasia(HD)
Bewegungsapparat
Hip dysplasia is an inherited skeletal disorder where the ball and socket of the hip joint do not fit together properly. Instead of sliding smoothly, the bones rub and grind against each other, wearing down the protective cartilage. Over time, this chronic friction causes joint instability, painful inflammation, and progressive arthritis, which is the gradual wear and tear of the joint.
Roentgen · Passing: FCI-Grad A oder B (frei/Grenzfall) oder PennHIP DI ≤ 0,40
Patellar Luxation(PL)
Bewegungsapparat
Patellar luxation, also known as a luxating patella, is a physical condition affecting the knee joint where the kneecap slips out of its normal groove. This misalignment interferes with the mechanical movement of the hind leg and can cause the joint to lock. Over time, this abnormal friction can lead to painful joint wear and tear, known as osteoarthritis.
Physisch · Passing: Grad 0 (frei)
Cervical vertebral compressive myelopathy(CVCM)
Bewegungsapparat
Cervical vertebral compressive myelopathy, commonly known as Wobbler syndrome, is a condition affecting the spine where the spinal cord in the neck becomes pinched. This compression is caused by malformed neck vertebrae or slipping discs between the bones. Over time, the constant pressure damages the nerve pathways that carry signals from the brain to the limbs.
Roentgen
Color Dilution Alopecia (CDA)(CDA)
Haut und Fell
Color Dilution Alopecia is a genetic skin disorder that affects dogs with diluted coat colors, such as blue, fawn, or lilac. It is caused by an abnormal distribution of pigment within the hair shafts, which makes the hair brittle and prone to breaking. This structural weakness leads to progressive hair loss and leaves the skin more vulnerable to irritation.
Haut
Sebaceous Adenitis(SA)
Haut und Fell
Sebaceous adenitis is an inflammatory skin disorder where the dog's immune system mistakenly attacks and destroys the sebaceous glands, which are the glands responsible for producing natural skin oils. Without these oils, the skin loses its protective moisture barrier, leading to severe dryness and damage to the hair follicles.
Passing: Frei (unauffällige Hautbiopsie)
Atrial septal defect(ASD)
Herz
An atrial septal defect is a congenital heart condition where a hole exists in the wall, called the septum, that separates the two upper chambers of the heart. This opening allows blood to flow abnormally between these chambers, which can gradually place extra strain on both the heart and the lungs.
Tricuspid valve dysplasia(TVD)
Herz und Kreislauf
Tricuspid valve dysplasia is a congenital heart defect where the tricuspid valve, located on the right side of the heart, does not develop normally. This valve normally acts as a one-way gate, but its malformation prevents it from closing properly. As a result, blood leaks backward into the right atrium instead of flowing forward to the lungs, forcing the heart to work much harder.
Ultraschall
Hypothyroidism
Hormonelles und Stoffwechsel
Hypothyroidism is an endocrine disorder where the thyroid gland, located in the neck, fails to produce enough thyroid hormones. These hormones are essential for regulating the body's metabolic rate, which is the speed at which cells convert nutrients into energy. When hormone levels are too low, the dog's entire metabolism slows down, affecting multiple organ systems.
Koerperfluessigkeiten · Passing: Unauffällig (TgAA-negativ, T4/TSH im Normbereich)
Immune-mediated thrombocytopenia(IMT)
Immunsystem
Immune-mediated thrombocytopenia is an autoimmune disease where the dog's immune system mistakenly attacks and destroys its own blood platelets, which are cells essential for normal blood clotting. This destruction occurs primarily in the spleen and liver, leaving the body with too few platelets to stop bleeding. Without enough of these cells, spontaneous and potentially severe bleeding can occur throughout the body.
Koerperfluessigkeiten
Degenerative Myelopathy(DM)
Nervensystem
Degenerative Myelopathy is a progressive disease of the spinal cord where the protective sheath around the nerves slowly breaks down. This deterioration disrupts the vital communication signals between the brain and the muscles of the hind limbs. Over time, this lack of signal transmission leads to a complete loss of muscle control in the back legs.
DNA
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physisch
Neonatal Encephalopathy with Seizures(NEWS)
Nervensystem
This is a severe, inherited brain disorder that affects newborn puppies, caused by an autosomal-recessive genetic mutation. It leads to abnormal development and degeneration of the central nervous system, which controls the body's movements and mental functions. Because it is inherited recessively, a puppy must inherit the mutated gene from both parents to be affected.
Roentgen
Deafness
Nervensystem
Deafness is a partial or complete loss of hearing that affects the nervous system and auditory pathways. It is often hereditary and frequently linked to specific coat pigmentation genes, such as the merle or piebald genes, which can affect the development of the inner ear. This genetic form of deafness results from a lack of pigment cells in the inner ear, leading to the degeneration of vital sensory cells.
Hoeren
Cerebellar abiotrophy(CA)
Nervensystem
Cerebellar abiotrophy is an inherited neurological disorder affecting the brain, specifically the cerebellum, which regulates balance and movement coordination. In affected dogs, the nerve cells in this region prematurely degenerate and die off. This progressive cell loss disrupts the brain's ability to control smooth physical movements.
DNA
Von Willebrand disease type I(vWD1)
Von Willebrand Disease Type I is an inherited bleeding disorder that affects the blood's ability to clot properly. It is caused by a deficiency in von Willebrand factor, a specific protein that helps blood platelets stick together to plug damaged blood vessels. Because this is an autosomal-dominant condition, a dog only needs to inherit one copy of the mutated gene to potentially show symptoms.
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every mandatory and recommended test plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Hip dysplasia (HD-FCI)
Both parents must be tested for Hip dysplasia (HD-FCI) and show a passing result.
We compile mandatory tests from official breed regulations and veterinary databases — and cross-check every uploaded certificate against the dog's profile using AI.
L1 = mandatory under breed-club regulations. L2 = recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are AI-extracted and checked for date, result, and consistency with the dog's profile — with our team reviewing anything inconclusive.
0 tests are currently mandatory under the relevant breed-club regulations. The most common are —. Every test must be completed before mating, and the result must fall within the threshold defined by the regulation.
Self-check
Answer 6 quick questions about your everyday life and see how well the Sheepadoodle fits you — including an honest cost estimate per month, per year, and across the dog's lifetime.
See breeders who have already uploaded their mandatory tests for verification.
View verified breeders