P2RY12-related platelet dysfunction · P2RY12 thrombopathia · Thrombozytopathie (P2RY12) · Platelet receptor P2RY12 defect · P2RY12-Defekt · P2RY12 receptor defect · Thrombozytopathie beim Grossen Schweizer Sennenhund · Platelet ADP receptor defect · P2RY12-associated bleeding disorder · P2Y12 receptor deficiency · ADP receptor thrombopathy · Selective platelet ADP receptor defect · Thrombozyten-ADP-Rezeptordefekt
This is an inherited blood clotting disorder affecting the circulatory system, specifically the blood platelets (thrombocytes). A genetic defect in the P2RY12 receptor prevents these platelets from clumping together properly to form clots. As a result, the dog's body cannot efficiently stop bleeding after an injury or blood vessel damage.
Symptoms are typically first noticed during puppyhood, often starting during teething or after minor injuries. Owners may observe prolonged bleeding from small cuts, frequent nosebleeds, or unexplained bruising.
The condition is lifelong and cannot be cured, but it can be managed by avoiding rough play and trauma. Emergency treatments or support during necessary surgeries, such as blood transfusions, typically cost between 500 and 3,500 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Heart.