Hereditary spherocytosis is an inherited red blood cell disorder primarily documented in Golden Retrievers, caused by a deficiency in a structural protein called spectrin. This deficiency causes the red blood cells to become fragile and spherical instead of their normal disc shape, leading to their premature destruction. While this hereditary form is genetic, abnormally round red blood cells (spherocytes) are more commonly acquired as a feature of immune-mediated hemolytic anemia (IMHA).
Affected dogs typically show symptoms from a young age. Owners may notice extreme lethargy, pale gums, yellowing of the skin or eyes, and dark urine after physical exertion.
This lifelong condition is manageable rather than curable, requiring ongoing medical support and regular blood panels. In severe cases, blood transfusions may be necessary, with overall treatment costs ranging from 1,500 to 6,000 EUR.
More conditions affecting the Heart.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.