Health Testing Guide
Which tests are mandatory, how to spot responsible breeders — and what it costs when things go wrong.
For the Australian Shepherd we've compiled 4 tests required by Club für Australian Shepherd Deutschland e.V. (CASD) and 11 additionally recommended tests, drawn from breed-club regulations, the University of PEI (CIDD), and OMIA — weighted by severity and heritability.
View verified breedersWhat this grade means
In the Australian Shepherd, orthopaedic problems such as hip dysplasia (HD) and elbow dysplasia (ED), as well as the MDR1 gene defect (multidrug sensitivity) and hereditary eye problems, define the health profile. The Club für Australian Shepherd Deutschland e.V. (CASD) makes radiographic screenings for HD (A–B), ED (0–1), testing for the MDR1 defect, and an ophthalmological eye examination mandatory for breeding. Forward-thinking breeders additionally carry out genetic tests for progressive retinal atrophy and degenerative myelopathy, ensuring that carriers are only mated with clear partners, and also keep the risk of epilepsy in mind. Before buying, ask to see the HD and ED evaluations as well as complete MDR1 and eye examination results for both parent animals.
Every breed is susceptible to certain inherited conditions. Just like humans, dogs inherit predispositions from their parents. Responsible breeders screen their breeding dogs for these conditions and make informed mating decisions to reduce the risk passed on to puppies.
No — but it's the strongest tool we have. Diet, exercise, environment, and genetics all contribute to whether a dog develops a condition. When breeders use the right tests to identify risk in potential parents, the likelihood of many conditions appearing in the puppies drops significantly.
There's no one-size-fits-all here. For the Australian Shepherd, Club für Australian Shepherd Deutschland e.V. (CASD) requires 4 tests for breeding approval, plus 11 additional recommended tests. The specific tests and passing thresholds are detailed further below.
Keep in mind
Reliable screening tests still don't exist for many hereditary conditions, and tests for complex polygenic conditions don't always predict severity in the puppies. Even so, they're a powerful tool of responsible breeding.
There are two main types of health tests:
Screen the dog's DNA for known disease-causing mutations. Can be performed from puppyhood and give a binary result (clear / carrier / affected).
Clinical and imaging exams like X-ray, ultrasound, or ophthalmoscopy. They show how a predisposition actually manifests — usually only conclusive after 12–18 months.
We group breeding programs into three levels based on testing depth. Ask your breeder directly which level they meet.
A breeder at the Great level meets the Good level and performs 11 additional clinically recommended screenings that reduce risk in this breed.
In addition to Good:
Collie eye anomaly (CEA)(CEA)
Augen
Collie Eye Anomaly is an inherited developmental defect affecting the eye, specifically the retina (the light-sensitive tissue at the back of the eye) and the choroid (the underlying layer of blood vessels). This genetic condition causes these structures to develop abnormally before birth. It is primarily seen in herding breeds and is inherited in an autosomal recessive manner.
Passing: clear or carrier
Cataract(HC)
Augen
A cataract is a progressive clouding of the lens inside the dog's eye, which is the clear structure that focuses light onto the retina at the back of the eye. When the lens becomes cloudy or opaque, it blocks light from entering, gradually impairing the dog's vision. If left untreated, this condition can eventually lead to complete blindness in the affected eye.
Eye examination · Passing: result on file
Microphthalmia
Augen
Microphthalmia is a congenital developmental disorder of the visual system where one or both of a dog's eyeballs are abnormally small. This structural defect occurs during embryonic development and is often accompanied by other eye abnormalities, such as cataracts, which are cloudy areas in the lens of the eye. Because the eyeball itself is underdeveloped, the surrounding eyelids may also appear droopy or misaligned.
Passing: clear
Pannus (Chronic Superficial Keratitis)(CSK)
Augen
Pannus, or chronic superficial keratitis, is an immune-mediated disease affecting the cornea, which is the clear outer surface of the eye. In this condition, the dog's immune system mistakenly attacks the cornea, causing blood vessels and dark pigment to grow across it. This process is worsened by exposure to ultraviolet (UV) light and can eventually block the dog's vision.
Eye examination · Passing: clear
Progressive Retinal Atrophy (PRA)(PRA)
Augen
Progressive Retinal Atrophy (PRA) is an inherited eye disease that affects the retina, which is the light-sensitive layer of tissue at the back of the eye. In this condition, the specialized cells responsible for detecting light, known as photoreceptors, gradually degenerate and die. Because these cells cannot recover or be replaced, the disease slowly but inevitably leads to complete blindness.
Passing: clear or carrier
Patellar Luxation(PL)
Bewegungsapparat
Patellar luxation, also known as a luxating patella, is a physical condition affecting the knee joint where the kneecap slips out of its normal groove. This misalignment interferes with the mechanical movement of the hind leg and can cause the joint to lock. Over time, this abnormal friction can lead to painful joint wear and tear, known as osteoarthritis.
Physical examination · Passing: PL 0–1
Merle coat pattern(M)
Haut und Fell
The merle coat pattern is caused by an autosomal-dominant mutation in the PMEL gene, which affects pigment-producing cells in the skin, eyes, and inner ears. When a dog inherits two copies of this gene, a condition known as double merle, it disrupts the normal development of these sensory organs. This genetic defect can lead to severe structural abnormalities in both the auditory and visual systems.
Passing: clear or carrier
Heart disease
Herz
Heart disease refers to structural or functional abnormalities of the heart muscle, valves, or electrical system that impair its ability to pump blood effectively. This reduced pumping efficiency prevents the cardiovascular system from delivering adequate oxygen and nutrients to the body's tissues. Some forms are congenital, meaning present from birth, while others are acquired over time due to wear or genetic factors.
Physical examination · Passing: normal
Congenital deafness(CHSD)
Nervensystem
Congenital deafness is a hereditary hearing loss present from birth that affects the inner ear's sensory cells, preventing sound signals from reaching the brain. It is usually genetic, occurs more often in certain breeds and is frequently linked to coat patterns such as merle or piebald.
Physical examination · Passing: hearing in both ears
Degenerative Myelopathy(DM)
Nervensystem
Degenerative Myelopathy is a progressive disease of the spinal cord where the protective sheath around the nerves slowly breaks down. This deterioration disrupts the vital communication signals between the brain and the muscles of the hind limbs. Over time, this lack of signal transmission leads to a complete loss of muscle control in the back legs.
DNA test · Passing: clear or carrier
Epilepsy(IE)
Nervensystem
Epilepsy is a chronic disorder of the brain and nervous system where abnormal electrical activity causes sudden, temporary disruptions in normal brain function. These disruptions lead to repeated seizures, which are involuntary changes in body movement, sensation, or behavior. Because the underlying cause is often complex, the brain's electrical signaling remains permanently prone to these sudden misfires.
Physical examination · Passing: {"resultNotOk": "Disease present"}
Not health tests, but required for breeding: the club asks for these results too. They don't count toward the risks or the rating.
DNA-Identitätsnachweis
Required by Club für Australian Shepherd Deutschland e.V. (CASD)
Acceptable result: Welpe muss gechipt sein
Wesensbeurteilung
Required by Club für Australian Shepherd Deutschland e.V. (CASD)
Acceptable result: Erfolgreiche Teilnahme
These levels are a comparison framework, not an official certification. They help compare breeding programs at a glance.
A complete checklist with every core-standard and additionally recommended test, plus identity and rearing questions — take it with you.
Open the full checklistFor breeders
Machine-readable mating rules, minimum ages, scoring schemes, and what's required for HonestDog verification — as a printable guide.
Example rule — Elbow Dysplasia
Both parents must be ED 0–1 or better.
We take mandatory tests from official breed regulations, build the recommended health standard from veterinary databases — and cross-check every uploaded certificate against the dog's profile using AI.
L1 = core standard: the club's required tests where its rules set them, otherwise the recommended health standard for the breed. L2 = additionally recommended or clinically indicated. L3 = lower prevalence. Every assignment carries a source and confidence rating.
VDH breeding regulations, CIDD (University of PEI), OMIA (University of Sydney), curated veterinary input.
Uploaded certificates are read by AI and checked for date, result, and consistency with the dog's profile — our team reviews anything inconclusive.
Not across the board. But these traits can play a role in the Australian Shepherd: Merle & double merle. Depending on the line, color or pairing, that is an extreme-breeding risk – what to look out for is explained on the linked pages.
Self-check
Answer 6 quick questions about your everyday life and see how well the Australian Shepherd fits you — including an honest cost estimate per month, per year, and across the dog's lifetime.
See breeders who have already uploaded their health test results for verification.
View verified breeders