Aneuploidy, monosomy, sex chromosome(XO)
Monosomy X · Canine Turner Syndrome · X0 Genotype · Sex Chromosome Monosomy · Turner-Syndrom beim Hund · Chromosomale Aneuploidie
What it is
This is a rare genetic condition where a female dog is born missing one of her two sex chromosomes, resulting in a single X chromosome instead of the normal pair. This chromosomal imbalance directly affects the development of the reproductive organs and the endocrine, or hormonal, system. Because the ovaries do not develop properly, the dog cannot produce normal levels of reproductive hormones.
How it presents
Owners typically notice that the dog is unusually small for her breed and fails to go into heat as she reaches young adulthood. Because of the abnormal reproductive development, these dogs are also completely infertile.
Treatment
There is no cure for this genetic condition, but it generally does not require intensive lifelong treatment unless other internal organs are malformed. Diagnostic confirmation using karyotyping, a specialized test to analyze the chromosomes, along with initial supportive care typically costs between 400 and 1500 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.