Aneuploidy, trisomy, sex chromosome XXX(XXX)
Triple X Syndrome · Trisomy X · Sex Chromosome Aneuploidy XXX · 47,XXX in dogs · Triple-X-Syndrom
What it is
This is a genetic condition where a female dog is born with three X chromosomes instead of the normal two. This extra genetic material primarily affects the development and function of the reproductive system. The condition is diagnosed using a laboratory test called karyotyping, which analyzes the dog's physical chromosomes.
How it presents
Most affected dogs show no outward signs of illness and live normal lifespans. Owners typically only notice symptoms when the dog reaches sexual maturity, which can include irregular heat cycles, a complete absence of heat, or infertility.
Treatment
There is no way to correct this chromosomal variation, but treatment is rarely needed as it does not impact overall health. Expected costs range from 150 to 1000 EUR, which covers the diagnostic karyotyping test and a routine spay procedure if advised by a veterinarian.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.