Glioma susceptibility
Also known as: Glioma predisposition · Brain tumor susceptibility · Gliom-Prädisposition · Anfälligkeit für Hirntumore · Genetic susceptibility to glioma
Overview
What it is
Glioma susceptibility is a complex genetic predisposition that increases a dog's risk of developing gliomas, which are malignant tumors of the brain and spinal cord. These tumors arise from glial cells, which are the supportive cells that surround and protect neurons in the central nervous system. Because this is a complex trait, factors other than genes likely also play a role in its development.
How it presents
Symptoms typically emerge in middle-aged to older dogs as the tumor grows and presses on brain tissue. Owners may notice seizures, sudden behavioral or personality changes, vision loss, or difficulty with balance and coordination.
Treatment
While these brain tumors are generally incurable, palliative treatments such as medications, surgery, or radiation therapy can help manage symptoms and extend quality of life. These supportive therapies are typically lifelong and can be costly, with treatment expenses generally ranging from 1,500 to 8,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment costs. Actual costs depend on severity, clinic and region.
Frequently asked questions
What is Glioma susceptibility?
Glioma susceptibility is a complex genetic predisposition that increases a dog's risk of developing gliomas, which are malignant tumors of the brain and spinal cord. These tumors arise from glial cells, which are the supportive cells that surround and protect neurons in the central nervous system. Because this is a complex trait, factors other than genes likely also play a role in its development.
How is Glioma susceptibility tested?
Various clinical and genetic tests are used depending on the breed and presentation.
Which breeds are most affected?
This condition isn't tied to a specific breed in our database.