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HighGeneral / metabolicAutosomal recessive

Hereditary myopathy - Labrador retriever/Bouviers des Flandres myopathy(CNM)

Centronuclear Myopathy · Hereditary Myopathy of the Labrador Retriever · HMLR · Labrador-Myopathie · Zentronukleäre Myopathie · Hereditary Myopathy · Angeborene Myopathie · Myopathy, congenital · Myopathie · Hereditäre Myopathie · Muskeldystrophie · Muscular Dystrophy · Hereditary Myopathy of Labrador Retrievers · CNM-Myopathie · Erbliche Myopathie des Labrador Retrievers · Centronucleäre Myopathie · Hereditäre Myopathie des Labrador Retrievers · CNM-HACD1

What it is

This is an inherited muscle disease affecting the skeletal muscles of Labrador Retrievers and Bouviers des Flandres. It is caused by a genetic defect that prevents muscle fibers from developing normally, leading to progressive muscle wasting where the muscles gradually shrink and weaken.

How it presents

Symptoms typically appear in puppies between 2 and 5 months of age. Owners will usually notice an unusual 'bunny-hopping' gait, general muscle weakness, and rapid fatigue that worsens with cold temperatures or stress.

Treatment

While the disease is incurable, it often stabilizes in adulthood. Lifelong supportive care, including physical therapy and specialized dietary management, is required and typically costs between €1,500 and €6,000.

How it's tested

No established test is currently catalogued for this condition.

Affected breeds

  • Aussiedor (Australian Shepherd x Labrador)
    Aussiedor (Australian Shepherd x Labrador)
    Recommended
  • Labrador Retriever
    Labrador Retriever
    Recommended

Treatment cost

€1,500 – €6,000

Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.

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