Mucopolysaccharidose Typ II · Hunter Syndrome · Iduronate-2-Sulfatase Deficiency · Lysosomale Speicherkrankheit Typ II
Mucopolysaccharidosis II (MPS II) is a severe, inherited metabolic disorder caused by a deficiency in an enzyme needed to break down complex sugar molecules. Without this enzyme, these sugars build up inside cells, causing progressive damage to multiple organ systems, including the skeleton and the nervous system. This condition is inherited in an X-linked manner, meaning it primarily affects male dogs.
Symptoms typically become noticeable in early puppyhood. Owners may observe stunted growth, skeletal deformities, cloudy eyes, and progressive difficulty walking or coordinating movements.
There is no cure for this progressive disease, and treatment is limited to lifelong supportive care to manage pain and maintain comfort. Supportive veterinary care typically costs between 1,000 and 5,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.