Mucopolysaccharidosis Type IIIB · Sanfilippo Syndrome B · Sanfilippo Type B · NAGLU deficiency
Mucopolysaccharidosis IIIB is an inherited lysosomal storage disease that primarily affects the brain and nervous system. It is caused by a deficiency in a specific enzyme needed to break down complex sugar molecules. Without this enzyme, these sugars accumulate inside the body's cells, leading to progressive cellular damage.
Symptoms typically become noticeable between 2 and 4 years of age. Owners may observe progressive neurological issues, such as tremors, a loss of balance, coordination difficulties, and changes in the dog's temperament.
There is no cure for this condition, and treatment is limited to supportive care to keep the dog comfortable. Managing these symptoms throughout the dog's life typically costs between 1,000 and 3,500 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.