Niemann-Pick-Krankheit Typ A · Sphingomyelinlipidose · Acid Sphingomyelinase Deficiency · ASMD · Canine Niemann-Pick Disease Type A
Niemann-Pick disease type A is an inherited metabolic disorder where the lack of a vital enzyme prevents the body from breaking down certain fats. Because of this deficiency, these fats build up to toxic levels inside cells, primarily damaging the nervous system, liver, and spleen. This progressive accumulation leads to widespread cell damage and severe organ dysfunction.
Affected puppies typically begin showing symptoms within the first few months of life, starting with mild coordination issues and muscle weakness. Owners will quickly notice worsening tremors, difficulty standing, and a rapid decline in overall mobility.
There is no cure for this disease, and veterinary care is limited to supportive and palliative therapy to maintain comfort. Managing the symptoms and providing end-of-life care typically costs between 500 and 2000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.