Pelger-Huët-Anomalie · Pelger-Huet-Anomalie · Pelger's anomaly · Congenital hyposegmentation of granulocytes · Pelger-Huet-Anomalie der Leukozyten · Pelger-Huët Anomaly · Pelger-Huet Anomalie · Granulocyte Hyposegmentation · Pelger-Huet anomaly of granulocytes
The Pelger-Huet anomaly is a harmless, inherited variation affecting the white blood cells, specifically a type of immune cell called granulocytes. In affected dogs, the nuclei of these cells do not segment or mature into their typical multi-lobed shape, though they continue to function completely normally. This condition is usually discovered by chance during routine blood tests and does not harm the dog's immune system.
Dogs with one copy of the gene show no symptoms, are entirely healthy, and have a normal lifespan from birth. However, puppies that inherit the gene from both parents typically die before or shortly after birth due to severe skeletal defects.
No treatment is necessary for affected dogs because this variation is harmless and does not affect their health. There are no associated medical costs, resulting in a lifetime treatment cost of 0 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.