Skeletal Dysplasia 3 · PCYT1A-related skeletal dysplasia · PCYT1A dwarfism · Skelettdysplasie Typ 3 · SD3 dwarfism
Skeletal dysplasia 3 (SD3) is an inherited genetic disorder of the skeletal system caused by a mutation in the PCYT1A gene. This mutation impairs the normal longitudinal growth of the limb bones, resulting in disproportionate dwarfism, a condition where the legs are abnormally short compared to the rest of the body.
Signs are visible during the puppy stage, as affected dogs develop disproportionately short legs relative to their body size. Over time, this abnormal bone structure can lead to joint pain, restricted mobility, and premature osteoarthritis.
While there is no cure, the condition is managed lifelong through pain relief, joint support, and physiotherapy. The estimated cost for this ongoing supportive care ranges from 1,500 to 5,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.