Alaskan Husky
SLC19A3 encephalopathy · Subacute necrotizing encephalomyelopathy · Thiamine transporter 2 deficiency · AHE of Alaskan Huskies · SLC19A3-associated encephalopathy
Alaskan Husky Encephalopathy is an inherited brain disease caused by a genetic mutation that disrupts how the body transports thiamine (vitamin B1). Without proper thiamine transport, the brain cannot process energy correctly, leading to progressive damage to nerve tissues. This is an autosomal-recessive condition, meaning a puppy must inherit the mutated gene from both parents to develop the disease.
Symptoms typically appear in young dogs between a few months and two years of age. Owners may notice seizures, sudden blindness, difficulty coordinating movements, and unusual behavioral changes.
There is no cure for this condition, and supportive care to manage symptoms typically costs between 1,000 and 3,000 EUR. Because the disease is progressive and severely impacts quality of life, humane euthanasia is often eventually required.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.