Alpha-1-Antitrypsin-Mangel · AAT deficiency · Alpha-1 protease inhibitor deficiency · A1ATD
This condition is a deficiency of alpha-1-antitrypsin, a protective protein that normally stops the body's own enzymes from breaking down healthy tissues. Without enough of this protein, the enzymes cause progressive damage to the liver. A clinical serum test is used to confirm the diagnosis by measuring the level of this protein in the blood.
Owners typically notice signs of liver disease, such as a loss of appetite, vomiting, yellowing of the skin and gums, and a swollen belly from fluid buildup. These symptoms usually begin to appear gradually during middle age.
There is no cure, but the condition can be managed lifelong with a specialized diet, liver-protective supplements, and supportive therapies. Lifetime management costs typically range from 1,500 to 6,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.