Grizzle · Domino · Grizzle coat color · Afghan grizzle · Saluki grizzle · MC1R Eg
Grizzle, also known as domino, is a harmless coat color pattern affecting the hair and skin pigment system, most commonly seen in sighthounds. It is inherited through a complex genetic process called multi-locus epistasis, meaning it requires a specific interaction between multiple genes—specifically MC1R, ASIP, and DEFB103—to express the pattern. This interaction regulates how dark and light pigments are distributed throughout the dog's coat.
Owners will notice a distinctive light-colored facial mask paired with a darker saddle or body coat. This purely visual pattern is visible from birth or early puppyhood and has no impact on the dog's physical health.
As this is a natural color variation and not a disease, no medical treatment is required. There are no associated veterinary costs, making the lifetime treatment cost 0 EUR.
More conditions affecting the Skin & coat.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.