Primary Hyperoxaluria Type 1 · Oxalosis I · AGXT deficiency · Primäre Hyperoxalurie Typ 1 · L-Alanine-Glyoxylate Aminotransferase Deficiency
Primary Hyperoxaluria Type I is a severe, inherited metabolic disorder affecting the liver and kidneys. Due to a missing liver enzyme, the body overproduces oxalic acid, which combines with calcium to form hard crystals in the kidneys. These crystals cause rapid, progressive damage to the urinary system and kidney tissues.
Affected puppies typically show signs of sudden kidney failure within their first few weeks or months of life. Owners may notice vomiting, a loss of appetite, extreme weakness, and a significant decrease in urination.
There is no cure for this condition, and treatment is limited to supportive care to keep the puppy comfortable. Due to the rapid progression of the disease, veterinary costs for diagnostics and short-term intensive care typically range from 500 to 2500 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.