ALOXE3-related ichthyosis · Autosomal recessive congenital ichthyosis · ARCI-ALOXE3 · Fischschuppenkrankheit · ALOXE3-Ichthyose
This is an inherited skin disorder caused by a genetic mutation that disrupts the skin's natural protective barrier. Without this barrier, the skin cannot retain moisture properly, leading to a severe buildup of dry, scaly skin cells, a process called hyperkeratosis. This condition specifically affects the outer layer of the skin and is inherited in an autosomal-recessive manner.
Owners will typically notice symptoms starting in puppyhood, characterized by dry skin, a coarse coat, and large, often dark scales. Affected dogs are also prone to frequent itching and secondary, painful skin infections.
While the condition is incurable and requires lifelong management, it can be controlled with regular medicated baths and moisturizing treatments. The lifetime cost of this supportive care typically ranges from 2,000 to 7,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Skin & coat.