Australian Kelpie
ACSL5 lipid malabsorption · Congenital lipid malabsorption · Fat malabsorption ACSL5-related · Intestinal lipid malabsorption · ACSL5-assoziierte Lipidmalabsorption
This is an inherited metabolic disorder of the digestive system, primarily affecting the Australian Kelpie breed, where the intestines cannot properly absorb or process dietary fats. It is caused by a specific genetic deletion involving the ACSL5 gene, which is essential for fat metabolism. Without this functioning gene, the body cannot utilize fats from food, leading to severe nutritional deficiencies.
Symptoms typically become noticeable in puppies shortly after weaning. Owners will usually observe chronic, fatty diarrhea, a dull coat, and a failure to gain weight despite the puppy having a ravenous appetite.
The condition is incurable and requires lifelong management with a strict, specialized low-fat diet and nutritional support. Lifetime management costs, including dietary adjustments and veterinary check-ups, typically range from 2,000 to 7,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.