Marfan-Syndrom · Canine Marfan Syndrome · FBN1 deficiency · Fibrillin-1 mutation
Marfan syndrome is a rare connective tissue disorder that weakens the body's structural support systems, particularly affecting the skeleton, eyes, and major blood vessels. In dogs, this condition is still poorly defined, and the exact genetic cause remains unknown, meaning no genetic test is currently available. The lack of proper tissue support leads to structural instability throughout the body.
Symptoms typically become noticeable within the first year of life and include unusually long limbs, loose or unstable joints, and visible eye abnormalities such as a displaced lens. Owners may also notice weakness or exercise intolerance due to underlying heart defects.
The condition is incurable and requires lifelong veterinary management, including regular heart monitoring and daily medications. Lifetime treatment and supportive care typically cost between €2,500 and €8,000.
More conditions affecting the General / metabolic.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.