Nodular dermatofibrosis and renal cystadenocarcinoma(RCND)
Hereditary multifocal renal cystadenocarcinoma and nodular dermatofibrosis · Noduläre Dermatofibrose des Schäferhundes · Renal cystadenocarcinoma and nodular dermatofibrosis · RCND syndrome · Nierenzellkarzinom und noduläre Dermatofibrose · Nierenzystadenokarzinom und noduläre Dermatofibrose
What it is
This is an inherited condition that affects both the skin and the kidneys. It causes non-cancerous, firm lumps of connective tissue (nodules) to form under the skin, while simultaneously causing fluid-filled sacs (cysts) and cancerous tumors to grow in the kidneys. Over time, these kidney abnormalities damage the organ's ability to filter waste from the blood.
How it presents
Owners usually first notice firm, painless skin bumps on the dog's legs or head, typically appearing between 3 and 6 years of age. As the kidney damage progresses, the dog may show signs of kidney failure, such as drinking and urinating much more than usual, vomiting, and losing weight.
Treatment
There is no cure for this condition, and treatment is lifelong and supportive to manage kidney failure and maintain quality of life. Supportive veterinary care and monitoring typically cost between 1,500 and 5,000 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.