Glasknochenkrankheit · Brittle Bone Disease · Canine Osteogenesis Imperfecta · Kollagendefekt der Knochen · Osteogenesis imperfecta Typ II · COL1A2-Osteogenesis-imperfecta · Osteogenesis imperfecta type III · COL1A2-related osteogenesis imperfecta · OI beim Dackel · Lobstein-Krankheit · Osteogenesis imperfecta in dogs
Osteogenesis imperfecta, commonly known as brittle bone disease, is an inherited genetic disorder that affects the skeletal system and connective tissues. It is caused by a defect in collagen production, which is the primary structural protein needed to build strong bones and teeth. Without proper collagen, the bones become extremely fragile and prone to breaking under normal, everyday activities.
Symptoms usually become noticeable during puppyhood, often as soon as the puppy starts moving around. Owners may observe unexplained bone fractures from minor impacts, severe pain, joint laxity, and stunted growth.
There is no cure for this severe condition, and treatment is limited to lifelong pain management, diagnostic imaging, and supportive care, which typically costs between 500 and 3,000 EUR. Due to the high frequency of painful fractures and poor quality of life, humane euthanasia is often considered.
More conditions affecting the General / metabolic.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.