Hereditary Footpad Hyperkeratosis · Focal Non-Epidermolytic Palmoplantar Keratoderma · Pfotenhyperkeratose · KRT16-related Hyperkeratosis · Digit Hyperkeratosis · FNEPPK · FNEPPK1 · Focal Non-Epidermolytic Palmoplantar Keratoderma-1
This is a hereditary skin disorder that affects the paw pads, caused by a genetic mutation that disrupts how keratin, a protective protein in the skin, is produced. This disruption leads to an abnormal, extreme thickening of the outer layer of the paw pads. It is specifically known to affect the Dogue de Bordeaux breed.
Owners will typically notice cracked, hardened, and thickened paw pads starting within the first few months of a puppy's life. This can cause discomfort or pain when walking, leading to lameness, and the cracked skin can sometimes develop secondary infections.
While there is no cure, the condition can be managed with lifelong daily care, including regular trimming of the excess hard tissue and applying moisturizing ointments. Managing this condition over a dog's lifetime typically costs between 1,000 and 4,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Skin & coat.