Hereditary Footpad Hyperkeratosis · GJB6-related footpad hyperkeratosis · Familiäre Pfotenballen-Hyperkeratose · Digitale Hyperkeratose
This genetic condition is caused by a mutation in the GJB6 gene, which affects the skin on a dog's paws. It leads to an overproduction of keratin, the tough protective protein that makes up the outer layer of the paw pads, causing them to become abnormally thick and hard.
Owners will typically notice symptoms within the first year of life as the paw pads become severely thickened, cracked, and develop hard, horn-like growths. These changes can cause discomfort, pain, and visible limping when the dog walks.
The condition is incurable and requires lifelong management, including regular trimming of the excess keratin and applying moisturizing ointments. Ongoing care is estimated to cost between 1,000 and 4,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Skin & coat.