SERCA1-deficiency · Brody-like syndrome in dogs · Pseudomyotonie · ATP2A1-Myopathie
Congenital pseudomyotonia, also known as paradoxical pseudomyotonia, is an inherited muscle disorder caused by a mutation in the SLC7A10 gene. This genetic defect affects the muscular system by preventing the muscles from relaxing normally after they contract. Unlike the bovine form of the disease, the canine version specifically impairs the chemical pathways needed for normal muscle relaxation.
Symptoms typically become visible during puppyhood, especially during periods of excitement or physical exertion. Owners will usually notice sudden muscle stiffness, a temporary 'freezing' of movement, or a stiff, stilted gait.
While there is no cure, this lifelong condition can be managed through medication, stress reduction, and controlled exercise. Lifetime management and veterinary care typically cost between 1,000 and 4,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the General / metabolic.