Continental Bulldog (National Breed)
Robinow-like syndrome · DVL2 mutation · DVL2-associated Robinow-like syndrome · Screw tail mutation
Robinow-like syndrome is an inherited developmental disorder that affects the skeletal system, specifically the spine, skull, and tail, due to a mutation in the DVL2 gene. This genetic mutation disrupts normal bone and cartilage development, leading to structural malformations such as a tightly coiled tail and abnormally shaped spinal bones called hemivertebrae. These spinal abnormalities can put pressure on the spinal cord, potentially damaging the nervous system.
Owners will typically notice physical signs starting in puppyhood, such as a severely kinked tail, a shortened muzzle, or an abnormal gait. As the dog grows, spinal compression can lead to more severe neurological symptoms, including back pain, weakness in the hind legs, or incontinence.
While the underlying genetic defect cannot be cured, symptoms can be managed with lifelong pain relief, physical therapy, or corrective spinal surgery in severe cases. Depending on whether conservative management or complex surgery is required, treatment costs typically range from 1,500 to 8,000 EUR.
More conditions affecting the General / metabolic.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.