KLF7-related early-onset adult deafness · Early-onset adult deafness KLF7 · KLF7-assoziierte Taubheit · KLF7 hearing loss · EOAD KLF7
This is an inherited form of deafness associated with a genetic variant in the KLF7 gene, which affects the development of the inner ear's sensory hair cells responsible for hearing. Because it is a candidate gene variant with incomplete penetrance, not every dog carrying the variant will actually develop hearing loss. It is primarily researched in Australian Stumpy Tail Cattle Dogs and is inherited in an autosomal dominant pattern.
Owners may notice that affected dogs do not respond to sounds, squeaky toys, or verbal commands, with signs typically becoming apparent during puppyhood or early adulthood. The hearing loss can affect one or both ears and may progress over time.
There is no cure for this genetic deafness, and the hearing loss is lifelong. Management focuses on supportive care and hand-signal training, with associated costs typically ranging from 150 to 600 EUR for diagnostic testing and training aids.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Ears.