English Setters are generally considered robust, athletic dogs, but they carry specific genetic predispositions affecting the joints, eyes, thyroid and hearing. One key issue, linked to the high proportion of white in the coat, is congenital deafness. The breed is also affected by joint problems such as hip dysplasia (HD), an underactive thyroid and inherited eye diseases such as progressive retinal atrophy (in particular the late-onset form rod-cone dysplasia 4, rcd4-PRA). In the breed club (e.g. the Verein für Pointer und Setter e.V.), testing for hip dysplasia, rcd4-PRA and deafness is mandatory; health-focused breeders also have their dogs tested for generalised PRA.
A health-focused breeder meets these risks with transparency and diagnostics: they have the parents’ hips, elbows and thyroid examined clinically and by X-ray to significantly reduce the risk for the offspring. DNA tests are available for rcd4-PRA and for the rare neurological disease neuronal ceroid lipofuscinosis (NCL). Such a DNA test reliably shows whether a parent is clear, a carrier or affected; a reputable breeder will only ever mate carriers with clear partners. In addition, each individual puppy’s hearing is measured by BAER testing (audiometry) before it goes to its new home.
The English Setter also has other breed-related health issues for which no routine DNA tests exist, including atopic dermatitis (skin allergies), eyelid abnormalities (ectropion/entropion), dry eye (keratoconjunctivitis sicca), the blood clotting disorder haemophilia and cutaneous asthenia (Ehlers-Danlos syndrome). In the first year of life, also take great care to give joint-friendly exercise during growth, and plan regular veterinary thyroid checks for the adult dog.