Primary Ciliary Dyskinesia · Immotile Cilia Syndrome · Ziliendyskinesie · NME5-related PCD
Primary ciliary dyskinesia is an inherited respiratory disease caused by a genetic mutation that affects the cilia, which are tiny, hair-like structures lining the airways. In affected dogs, these cilia are malformed or unable to move properly, preventing them from clearing mucus, dust, and bacteria out of the lungs and nasal passages. This failure of the respiratory clearance system leads to chronic airway irritation and recurrent infections.
Symptoms typically appear in puppyhood and include a chronic cough, thick nasal discharge, and recurrent bouts of pneumonia. Owners may also notice that affected puppies have difficulty breathing or tire more easily than their littermates.
This is an incurable, lifelong condition that requires daily supportive care, including inhalation therapy, mucus-thinning medications, and frequent antibiotics for secondary infections. Managing these chronic respiratory issues over the dog's lifetime is estimated to cost between 4,000 and 15,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
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