Progressive Retinal Atrophy, Cone-rod dystrophy 1 (American Pit Bull Terrier)(PRA-crd1)
Cone-rod dystrophy 1 · crd1 PRA · Progressive retinal atrophy crd1 · Zapfen-Stäbchen-Dystrophie 1 · PDE6B-PRA · crd1-PRA · PDE6B-crd1
What it is
Progressive Retinal Atrophy (crd1) is an inherited eye disease that affects the retina, which is the light-sensitive layer at the back of the eye. In affected dogs, the specialized sensory cells responsible for both day vision (cones) and night vision (rods) degenerate prematurely and irreversibly. This gradual breakdown of cells eventually prevents the eye from sending visual signals to the brain.
How it presents
Owners may first notice signs of vision loss, such as bumping into objects or disorientation in low light, starting as early as 10 weeks of age. The disease progresses rapidly, typically leading to complete blindness by one to two years of age.
Treatment
There is no cure for this condition, and management focuses on supportive care and environmental adjustments to help the dog adapt to blindness. Lifetime costs generally range from 300 to 1200 EUR, primarily covering veterinary ophthalmologist visits and safety aids.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.