Chondrodystrophy(CDDY)
Also known as: Chondrodystrophie · Chondrodystrophy and Intervertebral Disc Disease · CDDY/IVDD · Skeletal Dwarfism · Chondrodystrophie (CDDY) und Bandscheibenvorfall (IVDD) · …
Overview
What it is
Chondrodystrophy is an inherited genetic condition that affects the development of cartilage and bone, leading to shortened limbs. This abnormal growth also causes the cartilage in the spinal discs to harden and degenerate prematurely. This degeneration significantly increases the risk of painful spinal disc herniations, which occur when the cushioning discs between the vertebrae bulge or rupture.
How it presents
Owners will typically notice shortened legs relative to the dog's body, alongside sudden signs of back pain, reluctance to jump, or hind limb weakness and paralysis. These spinal symptoms frequently appear early in life, typically between 1 and 4 years of age.
Treatment
While the skeletal malformation itself is permanent, resulting disc herniations can be treated with emergency surgery, pain management, and rehabilitation. This treatment is costly, typically ranging from 2,000 to 9,000 EUR, and dogs may require lifelong care or physical therapy.
How it's tested
Labogen Komplettpaket (rassespezifisch)(Labogen-Panel)
Primary testDNA testRassespezifisches DNA-Panel (Labogen / Laboklin) — bündelt alle relevanten Erbkrankheiten der Rasse in einem Test.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Chondrodysplasie (CDPA) DNA-Test(CDPA)
Primary testDNA testEin Gentest, der das Vorhandensein des FGF4-Retrogens auf Chromosom 18 nachweist, welches fuer die Verkuerzung der Gliedmassen (Chondrodysplasie) verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
CDDY (FGF4-Retrogen) DNA-Test(CDDY)
Primary testDNA testEin molekularbiologischer DNA-Test zum Nachweis des FGF4-Retrogens auf Chromosom 12, welches mit Chondrodystrophie und einem erhoehten Risiko fuer Bandscheibenvorfaelle (IVDD) assoziiert ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
CDDY (Chondrodystrophie) und IVDD-Risiko Gentest(CDDY/IVDD)
Primary testDNA testDer Gentest identifiziert die FGF4-Retrogen-Insertion auf Chromosom 12, welche für die Verkürzung der Beine (Chondrodystrophie) und die vorzeitige Degeneration der Bandscheiben verantwortlich ist.
Issuing body: Labogen
Result scheme: Clear/Carrier/Affected
Feragen Komplettpaket (rassespezifisch)(Feragen-Panel)
DNA testRassespezifisches DNA-Panel (Feragen, Österreich) — gleiches Konzept wie Labogen.
Issuing body: Feragen
Result scheme: Clear/Carrier/Affected
Embark Breed + Health Panel(Embark)
DNA testUS-Anbieter; 250+ genetische Erkrankungen + Abstammung. Anerkennung in DE/AT variiert je nach VDH-Verein.
Issuing body: Embark
Result scheme: Clear/Carrier/Affected
MyDogDNA Panel(MyDogDNA)
DNA testGenoscoper-basiertes Panel (Mars Petcare). 200+ Erkrankungen + Rassenkomposition.
Issuing body: MyDogDNA
Result scheme: Clear/Carrier/Affected
Affected breeds
9 of 9 breeds
Mandatory testBasset Bleu de Gascogne
Mandatory testMiniature Dachshund
Mandatory testMiniature Long-haired Dachshund
Mandatory testMiniature Smooth-haired Dachshund
Mandatory testMiniature Wire-haired Dachshund
Mandatory testSmall Schwyz Hound
Mandatory testSmall Swiss Hound (Jura)
Mandatory testTeddy Roosevelt Terrier
RecommendedSmall Bernese Hound
Why is this linked to extreme breeding?
This condition can be tied to a trait dogs are bred for. These pages explain how it arises, which breeds are affected and how to recognise dogs bred for health.
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
Frequently asked
What is Chondrodystrophy?
Chondrodystrophy is an inherited genetic condition that affects the development of cartilage and bone, leading to shortened limbs. This abnormal growth also causes the cartilage in the spinal discs to harden and degenerate prematurely. This degeneration significantly increases the risk of painful spinal disc herniations, which occur when the cushioning discs between the vertebrae bulge or rupture.
How is Chondrodystrophy tested?
Tests currently in our database: Labogen Komplettpaket (rassespezifisch), Chondrodysplasie (CDPA) DNA-Test, CDDY (FGF4-Retrogen) DNA-Test, CDDY (Chondrodystrophie) und IVDD-Risiko Gentest, Feragen Komplettpaket (rassespezifisch), Embark Breed + Health Panel, MyDogDNA Panel.
Which breeds are most affected?
Most commonly affected: Basset Bleu de Gascogne, Miniature Dachshund, Miniature Long-haired Dachshund, Miniature Smooth-haired Dachshund, Miniature Wire-haired Dachshund, Small Schwyz Hound, Small Swiss Hound (Jura), Teddy Roosevelt Terrier.