GM2 Gangliosidosis · Tay-Sachs Disease in Japanese Chins · HEXA Deficiency · GM2-Gangliosidose Typ I · GM2-Gangliosidose Japan Chin
GM2 Gangliosidosis Type 1b is an inherited metabolic disorder that affects the central nervous system. It is caused by a deficiency in a vital enzyme, which prevents the body from breaking down certain fatty-sugar compounds called gangliosides. As a result, these substances build up to toxic levels inside the brain and nerve cells, causing progressive neurological damage.
Symptoms typically begin between 3 and 4 months of age, starting with coordination problems, tremors, and vision loss. These signs progress rapidly until the dog is no longer able to stand.
This condition is incurable and fatal, with veterinary care focusing entirely on comfort and palliative support. Managing the dog's comfort and eventual euthanasia typically costs between 500 and 2000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.