Alaskan Husky
GM1-Gangliosidose · Acid beta-galactosidase deficiency · GLB1 deficiency · Lysosomale Speicherkrankheit GM1 · Lysosomale Speicherkrankheit · Ganglioside storage disease
GM1 gangliosidosis is an inherited lysosomal storage disease that primarily affects the nervous system. It occurs when a deficiency in a specific enzyme, beta-galactosidase, prevents the body from breaking down certain fatty sugar compounds. Over time, these compounds build up to toxic levels inside cells, causing progressive damage to the brain and spinal cord.
Symptoms typically appear in puppies between 4 and 6 months of age, starting with tremors, muscle weakness, and difficulty coordinating movements. The condition progresses rapidly, eventually leading to blindness and seizures.
This disease is currently incurable and unfortunately fatal. Veterinary care is focused entirely on keeping the dog comfortable, with palliative care and humane euthanasia costs typically ranging from 500 to 2000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.
