Japanese Chin
Mandated by Japanese Chin Club of America / OFA CHIC
GM2 Gangliosidosis · Tay-Sachs Disease · GM2 Gangliosidosis Type I · Beta-Hexosaminidase A Deficiency · GM2-Gangliosidose Typ I · GM2-Gangliosidose · Hexosaminidase Deficiency · GM2 Gangliosidose · Canine Tay-Sachs Disease
This is an inherited metabolic disorder where a deficiency in the enzyme beta-hexosaminidase A causes harmful fatty substances to build up in the central nervous system. This buildup leads to progressive and irreversible damage to the brain and spinal cord cells. Because the cells cannot properly break down these waste products, the nervous system gradually stops functioning.
Symptoms typically appear within the first few months of life and progress rapidly. Owners will first notice neurological signs such as body tremors, difficulty coordinating movements, and a gradual loss of vision.
There is no cure for this condition, and treatment is limited to supportive and palliative care to keep the dog comfortable. Managing the symptoms and diagnostic testing typically costs between 500 and 2000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.