CYTB-related leukodystrophy · Mitochondrial leukodystrophy · Cytochrome b leukodystrophy · Mitochondriale Leukodystrophie · CYTB-Leukodystrophie · Canine spongiform leukoencephalomyelopathy · Shetland Sheepdog leukodystrophy
This is a severe hereditary disease of the nervous system caused by a defect in a mitochondrial gene, which is responsible for cellular energy production. This defect leads to the progressive breakdown of myelin, the protective fatty sheath that insulates nerve fibers in the brain. Without this protective coating, the brain cannot properly transmit electrical signals to the rest of the body.
Symptoms typically begin during puppyhood or adolescence. Owners may notice progressive coordination problems, muscle weakness, tremors, vision loss, and changes in behavior.
There is no cure for this condition, and treatment is limited to supportive care to keep the dog comfortable. Palliative management typically costs between 500 and 2500 EUR, and euthanasia is eventually necessary to prevent suffering.
More conditions affecting the Head / nervous system.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.