SERAC1-related multiple system degeneration · SERAC1-MSD · Multiple System Degeneration · SERAC1-associated neurodegeneration · Multisystemdegeneration beim Hund · Canine Multiple System Degeneration
This is a severe, inherited disorder of the nervous system caused by a genetic mutation in the SERAC1 gene. The mutation disrupts cellular lipid metabolism, which is the process cells use to break down and use fats. This disruption leads to progressive damage to nerve cells in both the brain and the spinal cord.
Affected dogs typically begin showing symptoms during puppyhood. Owners will notice rapidly worsening neurological signs, including coordination issues, tremors, balance problems, and changes in behavior.
There is no cure for this fatal condition, and treatment is limited to supportive care to keep the dog comfortable. Managing the symptoms and providing palliative care typically costs between 250 and 1000 EUR, though early euthanasia is often necessary to prevent suffering.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.