Necrotising meningoencephalitis(NME)
Also known as: Pug Dog Encephalitis · PDE · Nekrotisierende Meningoenzephalitis · Meningoenzephalitis der Mops-Hunde · Necrotizing meningoencephalitis
Overview
What it is
Necrotising meningoencephalitis is a severe, progressive inflammatory disease of the brain and its protective outer membranes, known as the meninges. It occurs when the dog's own immune system mistakenly attacks healthy nerve tissue, causing tissue death, or necrosis, in the brain. This condition primarily affects the central nervous system of certain small and toy dog breeds.
How it presents
Owners typically notice sudden neurological signs such as seizures, disorientation, blindness, or unusual behavioral changes. These symptoms most commonly first appear in dogs between 6 months and 7 years of age.
Treatment
The disease is incurable and requires lifelong medical management, including immunosuppressive therapies and anti-seizure medications. Ongoing veterinary care and treatment typically cost between €3,000 and €10,000.
How it's tested
Neurologische Untersuchung, MRT und Liquoranalyse(MRT/CSF)
Primary testClinical examDie Diagnose von MUO erfolgt klinisch durch eine Kombination aus einer neurologischen Untersuchung, einer Magnetresonanztomographie (MRT) des Gehirns und einer anschließenden Liquoruntersuchung (Gehirn-Rückenmarks-Flüssigkeit).
Issuing body: vet
Affected breeds
1 of 1 breeds
Treatment cost
Estimated range of typical treatment costs. Actual costs depend on severity, clinic and region.
Frequently asked questions
What is Necrotising meningoencephalitis?
Necrotising meningoencephalitis is a severe, progressive inflammatory disease of the brain and its protective outer membranes, known as the meninges. It occurs when the dog's own immune system mistakenly attacks healthy nerve tissue, causing tissue death, or necrosis, in the brain. This condition primarily affects the central nervous system of certain small and toy dog breeds.
How is Necrotising meningoencephalitis tested?
Tests currently in our database: Neurologische Untersuchung, MRT und Liquoranalyse.
Which breeds are most affected?
Most commonly affected: Pug.