MFN2-NAD · Neuroaxonale Dystrophie · Mitofusin-2 related neuroaxonal dystrophy · Canine neuroaxonal dystrophy MFN2
Neuroaxonal dystrophy (MFN2-related) is a severe, inherited neurological disorder that affects the nervous system of Giant Schnauzers and Schnauzer-Beagle crosses. It is caused by a genetic defect in the mitofusin-2 gene, which leads to abnormal swelling and progressive damage to the nerve fibers, known as axons, that transmit signals throughout the body. This damage prevents the brain and spinal cord from communicating properly with the muscles.
Symptoms typically begin at a young age, starting with mild coordination issues and a wobbly gait. Over time, owners will notice progressive muscle weakness, tremors, and a loss of balance, eventually making it difficult or impossible for the dog to stand or walk.
There is no cure or effective treatment for this progressive condition, and supportive care is limited to keeping the dog comfortable. Because the disease is severe and cannot be managed long-term, owners typically choose early euthanasia, keeping treatment costs at 0 EUR beyond initial diagnosis and compassionate end-of-life care.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.