Neuronal Ceroid Lipofuscinosis Type 2 · Batten Disease Type 2 · TPP1 Deficiency · Neuronal Ceroid-Lipofuszinose Typ 2 · NCL 2
Neuronal ceroid lipofuscinosis type 2 (NCL2) is an inherited metabolic disorder affecting the nervous system. It is caused by a deficiency in a specific enzyme, which prevents the body from breaking down cellular waste products. These waste materials build up inside the cells of the brain and the retina, the light-sensitive tissue at the back of the eye, leading to progressive cell death and severe neurological damage.
Owners typically notice symptoms between 1 and 2 years of age, starting with vision loss, uncoordinated movement, and changes in behavior. As the disease progresses, it leads to seizures, mental decline, and a significantly shortened lifespan.
There is no cure for this fatal condition, so treatment focuses entirely on supportive and palliative care to keep the dog comfortable. Managing these symptoms over the dog's remaining life typically costs between €1,500 and €5,000.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.