Neuronal Ceroid Lipofuscinosis Type 7 · NCL 7 · MFSD8-related NCL · Neuronal Ceroid-Lipofuscinosis 7 · Ceroid-Lipofuszinose Typ 7 · Neuronal Ceroid Lipofuscinosis MFSD8 · Neuronale Zeroidlipofuszinose Typ 7
Neuronal ceroid lipofuscinosis type 7 (NCL7) is an inherited metabolic disorder that affects the central nervous system. It occurs when a genetic mutation prevents cells from properly breaking down cellular waste, causing these waste products to build up and damage nerve cells in the brain. This buildup leads to the progressive loss of normal brain and nerve function.
Owners typically first notice symptoms in early adulthood, starting with vision loss, anxiety, behavioral changes, and coordination issues. These neurological signs rapidly worsen over time, leading to severe mobility and cognitive decline.
There is no cure for this fatal condition, and treatment is limited to supportive care to keep the dog comfortable. Managing symptoms and providing palliative care typically costs between 1,000 and 4,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.