Neuronal ceroid lipofuscinosis type 8 · CLN8 disease · Ceroid-Lipofuszinose Typ 8 · Canine NCL8 · Neuronal Ceroid Lipofuscinosis CLN8
Neuronal ceroid lipofuscinosis type 8 (NCL8) is an inherited metabolic disorder affecting the central nervous system. It is caused by a genetic defect that prevents cells from breaking down cellular waste products, leading to a harmful buildup in the brain's nerve cells. Over time, this accumulation causes progressive and irreversible damage to the brain tissue.
Symptoms typically appear between 1 and 2 years of age, starting with vision loss, coordination issues, and noticeable behavioral changes. As the disease advances, dogs often experience seizures and a severe decline in mental and physical capabilities.
There is no cure for this progressive disease, so treatment focuses entirely on palliative care and managing seizures with medication. Providing supportive care to keep the dog comfortable typically costs between 1,000 and 4,000 EUR.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.