Alaskan Malamute
Alaskan Malamute Polyneuropathy · Greyhound Polyneuropathy · GHPN · NDRG1-associated polyneuropathy · NDRG1-PN · NDRG1-related polyneuropathy · Hereditary Polyneuropathy in Alaskan Malamutes · Familiäre Polyneuropathie beim Alaskan Malamute · GP · GPN · NDRG1-related polyneuropathy in Greyhounds · Greyhound Neuropathy · Sensory and Motor Neuropathy · NDRG1-associated neuropathy · Greyhound-Polyneuropathie · Hereditäre Neuropathie beim Greyhound · Polyneuropathy, NDRG1-related
This is an inherited disorder of the peripheral nervous system where the protective outer coating of the nerves, known as the myelin sheath, gradually breaks down. Without this protective layer, the electrical signals traveling between the brain and the muscles are disrupted. This leads to a progressive loss of muscle control and coordination throughout the dog's body.
Symptoms typically appear before two years of age, starting with an abnormal gait, hind limb weakness, and muscle wasting. As the disease progresses, owners may also notice hoarseness, changes in barking, and breathing difficulties due to paralysis of the voice box.
There is no cure for this progressive condition, and treatment is limited to lifelong supportive care to manage symptoms. Supportive therapy typically costs between 1,000 and 4,000 EUR, though severe loss of quality of life often leads to a decision for early euthanasia.
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.
More conditions affecting the Head / nervous system.
