Progressive Retinal Atrophy, type 3, FAM161A-related(PRA3)
Progressive Retinal Atrophy Type 3 · PRA Type 3 · FAM161A-associated progressive retinal atrophy · Progressive Netzhautatrophie Typ 3 · Retinal atrophy, progressive, type 3, FAM161A-related
What it is
This is an inherited eye disease where the retina, the light-sensitive layer at the back of the eye, gradually breaks down. A genetic mutation in the FAM161A gene causes the progressive loss of photoreceptors, which are the specialized cells responsible for detecting light. Over time, this degeneration leads to irreversible vision loss.
How it presents
Owners typically first notice signs of night blindness, such as hesitation in the dark, with symptoms usually appearing between 4 and 7 years of age. As the disease progresses, the dog's peripheral vision narrows, eventually leading to complete blindness even in daylight.
Treatment
There is no cure for this condition, but it is painless and dogs usually adapt well to gradual vision loss. Management focuses on diagnostic confirmation and supportive lifestyle adjustments, with typical costs ranging from 300 to 1200 EUR.
How it's tested
Affected breeds
Treatment cost
Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.