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ModerateGeneral / metabolicAutosomal recessive

Disorders of sexual development - sex reversal(DSD)

Disorders of Sex Development · XX Sex Reversal · Geschlechtsumkehr · SRY-negative XX DSD · Hermaphroditismus · Intersexualität beim Hund · XX difference of sexual development, generic · XX DSD · XX disorder of sex development · XX Geschlechtsentwicklungsstörung · Female pseudohermaphroditism · Disorders of sexual development - sexual reversal

What it is

This is a congenital condition affecting the reproductive system where a dog's genetic sex (their chromosomes) does not match their physical gonads (internal reproductive organs like ovaries or testes) or external genitalia. This mismatch occurs during early development in the womb. Because it is inherited in an autosomal recessive pattern, a puppy must inherit the mutated gene from both parents to be affected.

How it presents

Owners typically notice signs as the dog reaches puberty or young adulthood, usually around 6 to 12 months of age. Affected dogs are infertile, may fail to show normal heat cycles, and can have unusual or ambiguous-looking external genitalia that are prone to chronic irritation or infections.

Treatment

The condition is treatable, typically requiring a one-time surgical removal of the malformed reproductive organs to prevent future tumors and infections. This surgery is a one-time expense that generally costs between 600 and 1800 EUR.

How it's tested

No established test is currently catalogued for this condition.

Affected breeds

  • American Staffordshire Terrier
    American Staffordshire Terrier
    Recommended
  • Beagle
    Beagle
    Recommended
  • German Shorthaired Pointer
    German Shorthaired Pointer
    Recommended
  • Miniature Pinscher
    Miniature Pinscher
    Recommended
  • Norwegian Elkhound
    Norwegian Elkhound
    Optional

Treatment cost

€600 – €1,800

Estimated range of typical treatment cost. Actual cost depends on severity, clinic and region.

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